Bempedoic acid has a novel mechanism of action that inhibits a cholesterol synthesis pathway by acting on ATP (adenosine triphosphate) citrate lyase, a citrate-degrading enzyme in the liver. Bempedoic ...
No writing assistance was utilized in the production of this manuscript. Homozygous familial hypercholesterolemia is a rare but significant cause of early-onset coronary heart disease. Early ...
The German Institute for Quality and Efficiency in Health Care (IQWiG) was commissioned by the Federal Joint Committee (G-BA) to assess the benefit of universal blood lipid screening for the early ...
Innovent Biologics, Inc. ("Innovent") (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of oncology, ...
Although evidence of benefit is based mainly on nonrandomized data, the procedure is widely accepted as first-line therapy for homozygous familial hypercholesterolemia and is increasingly used to ...
Background: Familial hypercholesterolemia (FH) is under-diagnosed and under-treated. Goals/Aims/Hypothesis: We developed an implementation strategy package to increase primary care awareness regarding ...