During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

In this study, we developed an agarose pad-based protocol to assay envelope stiffness by measuring population-averaged cell length before and after a hyperosmotic shock. Pad-based measurements ...

We found that ATK1 and ATK5 were rapidly concentrated toward unified polar foci when cells were under hyperosmotic conditions. Concomitantly, spindle poles became perfectly focused as if there were ...

Sorbitol is hyperosmotic, meaning it draws water into the colon from the tissues beside it to help move any stool along. It also softens the poop, making it easier to pass. Foods high in sorbitol ...

Medically reviewed by Jay N. Yepuri, MD Stool softeners, also known as emollient laxatives, are over-the-counter (OTC) ...