Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders ...

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their ...

Acquired resistance to PD-L1 inhibition can rewire the interferon-regulated secretory machinery in tumor cells, altering the ...

Prostate cancer and other cancers characterized by “cold” tumors could become more responsive to checkpoint blockade if UBA1 is inhibited.

In an interview, Vincent Law, of Moffitt Cancer Center, discussed a new study that offers hope for patients with melanoma ...

including the entry proteins ACE2 and transmembrane serine protease 2 (TMPRSS2); 21 proteins in the interferon-I (IFN-I) antiviral response pathway; and tethrin, a protein that suppresses new virion ...

The paradigm of stellate cell activation provides an important framework for defining sites/targets of antifibrotic therapy (Table; see [54] for review). These strategies include: (A) curing the ...

The country offers a good pathway for graduates because of their interest in conserving talents. Clear post-study permanent residency pathways make Australia one of the most sought-after ...