在肿瘤研究的浩瀚征程中，科学家们从未停止探索的脚步。肿瘤的特征之一是不受控制的细胞分裂，并在此过程中伴随着DNA复制、细胞周期蛋白的表达和激活、微管蛋白重组等细胞活动。一些小分子抑制剂，例如DNA烷化和交联剂、CDK抑制剂等可以高效地阻断上述过程，进 ...

Pyridostigmine bromide extended-release tablets: Alvogen and Rising Pharmaceuticals have both reported shortages of pyridostigmine bromide 180-milligram, extended-release tablets. Rising estimated ...

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University of California, San Diego, La Jolla, CALIFORNIA, United States ...

The P/B ratio shows how a stock's market price compares to its book value. It helps gauge whether a stock is undervalued or overvalued relative to its net assets.

Tumor necrosis factor-α (TNF-α)-induced RIP1/RIP3 (receptor-interacting protein kinase 1/receptor-interacting protein kinase 3)-mediated necroptosis has been proposed as an alternative strategy ...

1Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas. *Corresponding Author: Ann H. Klopp, Department of Radiation Oncology, University of Texas MD Anderson ...

Unfortunately, she developed pancytopenia 6 months after remission. Acute myeloblastic leukemia (AML), M5 type, was then diagnosed from bone marrow study, which has been treated with combined ...

Patients with acute promyelocytic leukemia (APL) often present with potentially life-threatening hemorrhagic diathesis. The underlying pathomechanisms of APL-associated coagulopathy are complex.

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States ...

Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM.