The following is a summary of “Patients with anti-PM/Scl-positive and idiopathic inflammatory myopathy resemble ...

Background: Cytokines play a vital role in the pathogenesis of idiopathic inflammatory myopathies (IIMs). Here, we investigated the expression of serum cytokine profiles in untreated IIMs and their ...

Myopathy refers to diseases of skeletal muscles (muscles connected to bone). The condition can be acute (meaning sudden, severe, and short-lasting) or chronic (persistent, recurrent, and often ...

Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Keywords: idiopathic inflammatory myopathies, myositis ...

The following is a summary of “Tacrolimus as first line therapy in a U.S. cohort of idiopathic inflammatory myopathies ...

Objectives Idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous autoimmune diseases. Intron retention (IR) serves as an important post-transcriptional and translational regulatory ...

A study has shed new light on the mechanisms behind idiopathic inflammatory myopathies (myositis), a group of systemic autoimmune disorders known for causing severe muscle weakness, fatigue ...

Explore how tumor necrosis factor inhibitors (TNFis) may reduce cardiovascular risks in patients with inflammatory arthritis, ...

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manchester.ac.uk Objectives Idiopathic inflammatory myopathies (IIM) are a spectrum of rare autoimmune diseases characterised clinically by muscle weakness and heterogeneous systemic organ involvement ...

Idiopathic inflammatory myopathies (IIMs) are associated with autoantibodies against nuclear and cytoplasmic antigens. Myositis-specific autoantibodies (MSAs) are specific to patients with IIMs.