脑胶质瘤是一种极具侵袭性和破坏性的原发性脑肿瘤，常规治疗手段对其效果不佳。患者在接受手术、放化疗等多学科治疗后，中位生存期仅约 15 个月。溶瘤病毒作为一种新兴的治疗方式，能选择性地在癌细胞内复制并杀死癌细胞，同时引发抗肿瘤免疫反应，在脑胶质瘤治疗中展现出一定潜力。例如，溶瘤腺病毒 Delta 24 - RGD 已完成 I 期研究，部分患者实现了长期生存；G207、HSV1716 ...

Researchers are now racing to come up with strategies to at least slow the spread of the disease in deer and reduce the ...

Australia Methods Following intracerebral inoculation with human origin prions the ileums of BalbC mice with clinical prion disease were assessed by Western immunoblot and immunohistochemical analysis ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

In patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting ...

The IP products were resolved by SDS-PAGE and immunoblot analysis. Freshly purified CD4 + T cells from healthy donors were pelleted with or without anti-CD3/28 Abs-coated microbeads (Dynabead Human ...

Introduction: Proinflammatory cytokines are implicated in pancreatic ß cell failure in type 1 and type 2 diabetes and are known to stimulate alternative RNA splicing and the expression of ...

Introduction Urban homeless populations in the UK have been shown to have high rates of active tuberculosis, but less is known about the prevalence of latent tuberculosis infection (LTBI). This study ...