在生物医学研究领域，诸如Jurkat T淋巴细胞、K562骨髓性白血病细胞、U2OS骨肉瘤细胞、COS-7猴肾细胞等多种难转细胞系，因其独特的生物学价值 ...

Dr Navya Verma Cancer is one of the most dreaded diseases of the 21th century and spreading further with continuance and increasing incidence. It is the third leading cause of death worldwide. It is a ...

*仅供医学专业人士阅读参考肿瘤微环境具有低氧和营养严重匮乏的特性，这是因为血管生成和营养物质扩散的速度跟不上肿瘤细胞的快速增殖。但令人没想到的是，极为有限的生存资源非但没有困住肿瘤细胞，反而成为它们进化出更强适应力的温床，肿瘤细胞展现出高度灵活的代谢 ...

由于新冠疫情的出现，mRNA疫苗被推上研究热潮，并有越来越多的学者开始关注mRNA疫苗在肿瘤中的治疗作用。此前国外已有研究证明在术后环境中利用个性化疫苗覆盖多种新抗原，并降低肿瘤负荷，是一种实用的mRNA治疗策略。然而，肿瘤疫苗是否可以用于高肿瘤负荷的晚期癌症患者尚不清楚。另外，目前还没有针对单一新抗原的疫苗策略的报道。分析所有已报道的免疫反应性新抗原的未发表数据表明，新抗原在个体之间重叠的比例极 ...

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...

The Attune ® Acoustic Focusing Flow Cytometer delivers higher sensitivity when you needed most. Precise alignment, even at high sample rates (up to 1 mL/min) will be maintained. Alternatively, a ...

What is Known About the Estrogen Deficiency of Menopause & Specific Autoimmune Diseases It is known that many natural, pathological and therapeutic conditions can change serum estrogen levels ...

The paper illustrates a valuable approach to generating TCR transgenic mice specific for known epitopes. Solid evidence validates the described pipeline for identification of TCRs from single-cell ...