Mouse embryonic stem cells (ESCs) are powerful tools for functional analysis of stem cell-related genes; however, complex gene manipulations, such as locus-targeted introduction of multiple genes and ...

Investigations into the molecular control of the quiescence-to-proliferation-to-differentiation continuum in the embryonic and adult brain have identified proneural genes encoding ...

It could also help other scientists choose which mouse models to use in their own aging-related work or carry out further studies to pinpoint individual genes that are associated with accelerated ...

Robert Darnell, a neuroscientist at Rockefeller University who had discovered the gene in 1993. He was startled because the gene appears to be essential to all mammals. A mouse engineered without ...

The included systems come from two different species (human and mouse), several tissues (brain, intestine, lung, stomach, breast, as well as embryonic tissue) and are associated with processes ranging ...

While the exterior of vertebrate bodies appears bilaterally symmetrical, internal organ positioning and morphology frequently exhibit left-right (L-R) asymmetries. In several vertebrates, including ...

Before you get a ranged weapon like a crossbow or bow, however, you might be wondering how to knock them down and plunder their contents. While nests contain eggs, they also have a chance to ...

Kebilidi is the first gene therapy approved by the FDA for administration directly into the brain, given via a cannula during a surgical procedure, and replaces the human dopa decarboxylase (DDC ...