To develop the next generation of in vivo T cell therapy, Novartis will leverage Vyriad's active targeting lentiviral vector ...

Using a lentiviral vector pseudotyped with Sendai virus fusion and hemagglutinin-neuraminidase ... For protein quantification, dPLA used oligonucleotide conjugated antibodies against GFP. Results ...

Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

Investigators said patients experienced adverse effects in line with those expected for myeloablative conditioning with ...

This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...

This issue highlights a high-throughput method for the rapid discovery of high-affinity antibodies ... in viral processes can constrain the lentiviral delivery and expression of Cas13, and ...

The cull also includes Aruvant's lentiviral sickle cell disease gene therapy ARU-1801 – in trials but with questionable commercial potential given progress with rival therapies – as well as ...

June, MD, PhD, Perelman School of Medicine, University of Pennsylvania, are co-recipients of the Pioneer Award, recognized for lentiviral gene therapy clinical trials and for their leadership and ...