Overall results of the lentiviral gene therapy show promise in overcoming a limitation of AAV-mediated approaches with the ability to bypass anti-AAV antibodies. There may be some critical ...

Among these, lentivirus-based vectors, derived from the HIV-1 retrovirus, are of growing interest in gene and cell therapy, particularly in immuno-oncology, due to their ability to infect dividing ...

A new vector system known as lentiviral vectors can permanently integrate the gene into dividing and non-dividing cells. The capacity of lentiviral vectors to reliably integrate at various genomic ...

In the original lentivirus vectors described by Naldini et al (Naldini et al., 1996a) (Naldini et al., 1996b) , the vector pCMVΔR8.2 supplies all but the HIV envelope in trans, the vector pMD.G is ...

and antibody engineering), plasmid and lentiviral vector process development for cell therapy, clinical plasmid production (such as gene therapy plasmid and cell therapy plasmid), GMP lentiviral ...