USA: Research shows that the melanocortin-4 receptor (MC4R) agonist setmelanotide effectively lowers BMI in children with ...

This discovery reveals a brain-gut pathway regulating food intake via ROS signaling. This study identifies parallel gut–brain pathways that fine-tune feeding. Distinct brainstem neurons and ...

Things haven’t been easy for 2019 Golden Valley High graduate Zack Chevalier, but that hasn’t stopped him from pursuing his ...

There are projections from the ARC to other hypothalamic nuclei, as well as the cerebral cortex and reward pathways ... that is inhibited by insulin and leptin. AgRP = Agouti-related protein ...

The proposed mechanisms of action of some of the nutraceutical supplements on the mammalian cholesterol pathway are shown in Figure 2. Virtually all studies have shown very high safety profiles ...

Deniz received her PhD from the University of Heidelberg. During her PhD work in the laboratory of Aurelio Teleman at the DKFZ, she uncovered a dedicated signaling pathway through which stearic acid ...

Dec. 11, 2024 — Older adults whose blood pressure fluctuates over time may be more likely to have problems with thinking and memory skills, according to a new study. The association was found in ...

Single-cell RNA sequencing of Kidney organoids revealed varying maturation rates in proximal tubule cells, with PPARα signaling linked ... of Smad2/3 in the TGFβ pathway, independent of Smad4 ...

Dec. 6, 2024 — People who climb too fast or too high risk acute altitude sickness, which can lead to life-threatening hypoxic brain injury. By using in vivo electrochemistry, researchers ...

Today's unavoidable sedentary lifestyles and easy access to high-calorie foods have led many to struggle with unwanted weight ...

The results of these experiments support the hypothesis of an intestinal signal induced by intraduodenal fat which ... may be involved in satiety pathways originating from the gastrointestinal tract.