Intravenous; LNP: Lipid nanoparticle ... demonstrated significantly higher transfection efficiency and lower toxicity to lung cells when compared with 25-kDa PEI [54] Use well-established natural ...

Dec. 11, 2024 — Scientists have made a significant breakthrough in understanding how 'bad' cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The ...

This article explores some of the challenges in developing cell lines for therapeutics, such as cell line stability, and how ...

As an alternative to the systemic delivery of immune checkpoint inhibitors, here the authors develop an in vivo gene-edit strategy using a conductive hydrogel-based electroporation system to ...

Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...