Tumor necrosis factor-related apoptosis-inducing ... constitutively expressed on murine natural killer (NK) cells in the liver and plays a substantial role in suppressing tumor metastasis.

TNF, tumor necrosis factor; AJ, adherens junctions; TJ, tight junctions; GJ, gap junctions; MLCK, myosin light chain kinase; PAMP, pathogen-associated molecular pattern; DAMP, damage-associated ...

The following are common causes of liver pain. Also known as alcohol-induced fatty liver disease, this form of liver disease is caused by drinking too much alcohol over time. There are three ...

Drug-induced liver injury (DILI) has become one of the major challenges of drug safety all ... interferon gamma; IL-6, interleukin 6; TNF-α, tumor necrosis factor-α; IL-10 interleukin 10; TGF-β, ...

Cirrhosis is a condition in which scar tissue gradually replaces your healthy liver cells. It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic ...

The liver is a large internal organ that is under your right ribs just beneath your right lung. It has two lobes (sections). The liver is made up mainly of cells called hepatocytes. It also has other ...

New York is facing its rat problem head-on. New York City is known for its towering skyscrapers and bustling streets, but lurking beneath the glitz and glamour of the city that never sleeps are 3 ...

Acute and chronic liver injury models were performed in wild type and Trem-2-/-mice. Primary liver cells from both genotypes of mice were isolated for in vitro experiments. Results TREM-2 was ...

State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing 100871, China ...

Some of these can be severe, such as leptospirosis, also called Weil’s disease, which can cause kidney and liver damage and even death without treatment. There is also increasing evidence rats ...

Akero Therapeutics reported Monday strong results from a nearly two-year, placebo-controlled study showing its drug efruxifermin reversed liver scarring in patients with cirrhosis caused by the ...