Successful research in targeted protein degradation depends not only on measurements at high sensitivity, speed and precision ...

Design Gain- and loss-of-function assays were performed to evaluate the effects of miR-541 on the malignant properties and autophagy of human HCC cells. Autophagy was quantified by western blotting of ...

Lipopolysaccharide (LPS) is the major component of the outer membrane of Gram-negative bacteria. This molecule can induce strong immune response and various biological effects. In mammals, TLR4 can ...

Anti-pA151R polyclonal antibody was produced in rabbit by immunization with recombinant pA151R. Double-Luciferase Reporter Assay Kit was from Promaga (USA). 2’3’-cGAMP, poly(dA:dT), and Lipofectamine ...

vanderbilt.edu Design Tff1-knockout (Tff1-KO) mice, immunohistochemistry, luciferase reporter, qRT-PCR, immunoblot, and phosphatase assays were used to examine the role of TFF1 on β-catenin signalling ...

After two years of unseasonably warm winters, conditions are looking to be perfect for ice anglers to get out and enjoy one of their favourite sports. Many are looking to get back into the game, to be ...

The following is a summary of “Role of NAT10-mediated ac4C acetylation of ENO1 mRNA in glycolysis and apoptosis in non-small ...

为解决 TP53 移码突变胃癌治疗难题，江南大学附属医院研究人员开展相关研究，发现 GSK690 可抑制 TP53 Frameshift NLS 胃癌细胞生长。该成果为这类患者提供新治疗策略，极具科研价值，推荐大家阅读。

为解决大肠杆菌生产流感 NP 时细菌 RNA 带来的安全及一致性问题，华中农业大学的研究人员开展相关研究。他们发现 NP 结合细菌 RNA 增强免疫反应，且开发的 NP 突变体可解决安全问题。该成果为通用流感疫苗研发提供新方向，值得一读。

UK Prime Minister Keir Starmer announced on Sunday plans for a UK-France initiative to craft a lasting peace plan for Ukraine, following the public debacle between US President Donald Trump and ...