MYC/MYCN是髓母细胞瘤（MB）中最常见的癌基因扩增，也是其高危（HR）疾病的主要生物标志物。然而，尽管许多携带MYC（N）扩增肿瘤的患者对治疗有耐药性，但也有一些患者能够实现长期生存。因此，研究者对MYC（N）扩增型MB内的临床生物学异质性进行 ...
A recent study investigates the relationship between exercise and the expression of MYC in skeletal muscles over time, ...
Researchers have long known that there is a relationship between the cancer-associated gene MYC (pronounced “Mick”) and ...
Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is ...
Results from dose escalation arms of Phase 1/2 study of MRT-2359 demonstrated a favorable safety profile and targeted levels of GSPT1 degradation ...
在本研究中，作者特异性突变Treg细胞的Lag3受体，揭示了Lag3通过PI3K-Akt通路抑制Myc的表达，从而支持Treg细胞免疫抑制功能的分子机制。 为了探究Lag3 ...
蛋白质纯化产品在Takara Bio公司众多家喻户晓的产品线中一直默默无闻，最近因Capturem™新型膜技术的推出而声名鹊起，今天就为大家挑选His、GST和Myc标签蛋白质纯化的三类具有代表性的产品进行 ...
Monte Rosa Therapeutics (GLUE) reported an update from its ongoing Phase 1/2 open-label, multicenter study of MRT-2359 in patients with ...
这篇文章揭示了Lag3共受体调节Treg细胞免疫抑制功能的具体机制，Lag3通过PI3K-Akt信号通路抑制Myc的表达，当Lag3缺失后Myc表达升高并激活下游代谢基因 ...
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