Northwestern Medicine scientists have discovered that inhibiting the GATA6 protein in mouse models of colon cancer reduced ...

Colon cancer has been on the rise in Americans under 50 for the last three decades, but it’s not exactly clear why.

A gene called high mobility group A1 (HMGA1) may be the key that opens the door to the development of colon cancer, according ...

The protective effect of anti-S100a9 antibody treatment was also observed in azoxymethane (AOM)/DSS-induced colitis-associated cancer (CAC) mouse model. The inflammatory response, tumor cell ...

A gene called high mobility group A1 (HMGA1) may be the key that opens the door to the development of colon cancer, according ...

We sought to define the impact of eosinophils that respond to acute phases of colitis in mice. Results Eosinophil-deficient mice developed significantly more severe colitis, and their colon tissues ...

Diet Is Main Risk Factor for Colon Cancer in Younger Adults, New Study Suggests Aug. 14, 2024 — A new study has identified diet-derived molecules called metabolites as main drivers of young ...

To identify the early steps that lead from gut inflammation to colon cancer, Resar and her team studied two mouse models with Apc mutations, the most common colon cancer-linked mutation in humans.

2012). Intestinal epithelial-cell-specific inhibition of NF-κB through conditional ablation of NEMO/IKKγ, the regulatory subunit of the IKK signaling complex essential for NF-κB activation, ...