Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

1Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang-si, Republic of Korea. 2Immuno-Oncology Branch, Graduate School of Cancer Science ...

The role of microglia in Alzheimer’s disease is debated. This paper shows that homeostatic microglia seed amyloid plaques in early disease stages and activated microglia compact plaques at later ...

University of Washington-led research, published in 2023, discovered microglia in the brains of people with Alzheimer's disease were in a pre-inflammatory state more frequently, making them less ...

Departments of Neurology and Neuroscience, University of Wisconsin-Madison, United States; ...

Dec. 9, 2024 — Researchers found that adolescents with more symptoms of gaming addiction showed lower brain activity in the region involved in decision-making and reward processing; this blunted ...

APP can be divided into three regions, AICD, E2 and E1, and each region performs different functions. Created with BioRender.com. Figure 3. Main effects of Aβ on neurons, microglia, and astrocytes in ...

Version of Record: This is the final version of the article. Some conceptual issues are still present. This is a mechanistic paper done completely in vitro, all references to the in vivo situation are ...

Dec. 11, 2024 — Gut microbiome composition during pregnancy has long-term effects on offspring stem cell growth and development, researchers report. Treating pregnant mice with a common gut ...

1 Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China 2 Department of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Early detection is warranted to improve ...