During PINK1- and Parkin-mediated mitophagy, autophagy adaptors are recruited to damaged mitochondria to promote their selective degradation. Autophagy adaptors such as optineurin (OPTN) and NDP52 ...

Share on Pinterest Scientists have found that mitochondria may play a role in triggering Crohn’s disease. Hernandez & Sorokina/Stocksy As of 2019, about 4.9 million people globally were living ...

Retraction Note: M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade. Retraction Note ...

According to a preclinical study conducted by Weill Cornell Medicine researchers, it may soon be feasible to detect whether ...

Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

and nucleoporin p62; the MND pattern mainly originates from autoantibodies directed to the Sp100 and the promyelocytic leukemia (PML) protein, antigens that are both localized in the NB.

Conclusion: NFPs regulate left ventricular compaction at both embryonic and postnatal stages, suggesting that LVNC can be both congenital and acquired. As LVNC mice progress, they develop dilated ...

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The manuscript presents a useful model for the field of endosome maturation, providing perspective on the role of the deubiquitinating enzyme UPS-50/USP8 in the process. The evidence presented in the ...