“We can engineer these NK cells to provide additional mechanisms or more activated cells that seem to be able to overcome those barriers.” Several challenges remain. Like CAR-T cells, NK cell ...

I formulated the missing-self hypothesis for natural killer (NK) cell recognition in the autumn of 1981, while writing the last chapter of my doctoral thesis. In 1975, I had joined the Department ...

Source: Sino Biological Inc. To mediate antibody-dependent cellular cytotoxicity (ADCC), NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA). A new area of cancer immunotherapy is ...

NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA) to mediate antibody-dependent cellular cytotoxicity (ADCC). Potentiating therapeutic mAb-mediated CD16 activation of NK cells is an ...

Physical exercise plays an important role in controlling disease, including cancer, due to its effect on the human body’s ...

CAR-NK therapy involves modifying NK cells using ... “But importantly, you also activate memory T cells. With this, if you can activate the immune system, then, once you’ve stopped the ...

Severe infection with Covid-19 has been found to produce a powerful cancer-fighting cell that can shrink tumors.

NK cells and gamma delta (γδ) T-cells – are activated to directly attack and kill tumor cells upon contact, while critically shaping the overall tumor microenvironment to be more permissive to ...

For solid tumors and hematological malignancies, CAR-NK cell treatment is a novel kind of cancer immunotherapy. CAR-NK cells work by killing cancer cells in a CAR-dependent way. CAR-NK cells and ...