Dragonfly's TriNKET compounds are designed to activate and direct NK and cytotoxic T cell killing against cancer cells. The platform has also attracted partnerships from other pharma groups ...
I formulated the missing-self hypothesis for natural killer (NK) cell recognition in the autumn of 1981, while writing the last chapter of my doctoral thesis. In 1975, I had joined the Department ...
Base Therapeutics has announced that its NK510 cell injection, the world's first zero-off-target base-edited NK cell product, has received IND approvals from both the U.S. FDA and China's NMPA for ...
so need to be activated before they attack cancer cells that present antigens. NK cells are part of the innate immune system, a first line of defense that doesn't need to be primed into action.
They provide convincing evidence for the effectiveness of IL-15/12-conditioned NK cells in this design, which was also critical for the authors being able to conclusively reveal the T cell-dependency ...
A research team behind a new study at the Hebrew University of Jerusalem has made an important breakthrough in understanding how immune cells known as T cells are activated. By using an innovative ...
Base Therapeutics announced that its in house-developed NK510 cell injection—the world’s first base-edited universal NK cell product—has received IND approvals in both China and the United States.
The underlying mechanisms linking ATP7B mutations to cholecystitis and natural killer cell exhaustion remain unclear. Specifically, it is not yet determined whether copper metabolism alterations ...