Systemic lupus erythematosus (SLE) is an autoimmune disease that sometimes involves the central nervous system in a condition known as neuropsychiatric SLE (NPSLE). Research in mice has shown that ...

We aimed to determine the levels of MFAP4 in a predominantly population-based cohort of systemic lupus erythematosus (SLE) patients, including neuropsychiatric SLE (NPSLE), and to evaluate MFAP4 as a ...

From a clinical point of view, NPSLE events can manifest as acute or recurrent, silent or overt and might be unnoticed or catastrophic. As examples, ischemic stroke might be asymptomatic or lead ...

NPSLE, neuropsychiatric systemic lupus erythematosus; LN, lunpus nephritis; RA, rheumatoid arthritis; CIA, collagen-induced arthritis. However, there is significant redundancy in the mechanisms that ...

对 LN 肾脏组织的其他研究还发现，PI3K - AKT 通路可能是潜在的治疗靶点，抑制该通路可以减轻肾脏炎症 。在神经精神性狼疮（NPSLE）的研究中，通过对小鼠模型的研究发现，大脑中干扰素通路增强，影响了细胞间的相互作用和神经系统的发育 。 空间转录组学在 ...

Abstract Background Patients with psoriatic arthritis (PsA) experience reduced physical function and impaired quality of life. Better patient-reported functional outcomes are found when lower disease ...

3 Center for Applied Statistics and School of Statistics, Renmin University of China, Beijing, China Objectives Open-labelled clinical trials suggested that low-dose IL-2 might be effective in ...