In general, chemotherapy medications work by attacking cells or by preventing them from growing and dividing. Cancer cells tend to grow and divide rapidly and uncontrollably, and many chemotherapy ...

Objectives Recently, necroptosis has attracted increasing attention in arthritis research ... inhibitor of nuclear factor kappa B (IκBα), Vimentin), Cell Signalling Technology (Danvers, USA; p-ERK, ...

This month's cover highlights the article Organotypic culture of human brain explants as a preclinical model for AI-driven antiviral studies by Emma Partiot, Barbara Gorda, Raphael Gaudin and ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

In their article published in Nature Methods, the researchers applied PERISCOPE to execute three whole-genome CRISPR screens to create an open-source atlas of cell morphology. The study is the ...

Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Katsura, ...

Iron is an essential micronutrient for cell survival and growth; however, excess of this metal drives ferroptosis. Although maternal iron imbalance and placental hypoxia are independent contributors ...

Shaanxi Key Laboratory of Macromolecular Science and Technology, Xi’an Key Laboratory of Hybrid Luminescent Materials and Photonic Device, MOE Key Laboratory of Material Physics and Chemistry under ...

Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China (X.H., J.Z., C.X., R.C., P.J., X.J., P.H ...

🌠 Navigate the cosmos of single-cell morphology with confidence — coSMicQC keeps your data on course! coSMicQC is a Python package to evaluate converted single-cell morphology outputs from CytoTable.

Populations of cells can be perturbed by various chemical and genetic treatments and the impact on the cells’ gene expression (transcription, i.e. mRNA levels) and morphology (in an image-based assay) ...