A computerized system that enables doses of drugs to be adjusted on the basis of the patient's GFR can certainly alleviate the risk of nephrotoxic effects in patients with renal insufficiency ...

This frequently manifests during drug development and/or in standard clinical care. Nephrotoxicity resulting from drug exposure has been estimated to contribute to 19–25% of all cases of acute ...

In clinical practice, strategies to reduce nephrotoxicity due to specific drugs are usually based on the avoidance of established risk factors, such as high doses. However, effective prevention of ...