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BMSCs 通过调控 SYNPO2 缓解新生儿缺氧缺血性脑病损伤:潜在的治疗新策略
经过深入研究,他们发现了令人振奋的结果:BMSCs 能够通过下调 SYNPO2 的表达,有效减轻神经元自噬损伤,改善 HIE 导致的神经功能障碍。这一发现意义非凡,为新生儿 HIE 的治疗开辟了新的道路,SYNPO2 有望成为治疗新生儿 HIE 的全新靶点,同时也为基于干细胞的治疗方案提供了崭新的理论依据。该研究成果发表在《Cell Death & Disease》期刊上。
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