To date, surgery is the only potentially curative treatment for gastric cancer; however, more than two-thirds of patients have unresectable disease upon diagnosis (4). Peritoneal carcinomatosis, ...

Metastatic brain cancer should be recognized as a distinct central nervous system (CNS) disease due to its unique molecular, genetic, and microenvironmental characteristics, rather than being ...

The U.S. Food and Drug Administration has approved Datroway (datopotamab deruxtecan-dlnk) for adult patients with unresectable or metastatic, hormone receptor (HR)-positive, human epidermal growth ...

So in addition to our backbone of aromatase inhibitor treatments and tamoxifen, we are converting metastatic breast cancer into a chronic disease by addressing resistance mechanisms. So the use of ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

In this review, we describe how physical cues in the tumor microenvironment are sensed by MICs and contribute to cancer metastasis. First, we highlight mechanical perturbations, by both solid and ...

Treatment (Rx) patterns and attrition rates in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC). Real world comparison of time-to-next-treatment (TTNT), ...

Patients with ERBB2-positive breast cancer and CNS-only metastasis are at a high risk for CNS-related death but have longer overall survival than those with concomitant extracranial metastases.

Brain metastases from prostate cancer (PC) seem to be more frequent than in the past, possibly because advances in the treatment of patients with castration-resistant PC have prolonged their survival.