Dysregulation of mitochondrial reactive oxygen species (mtROS) contributes to intestinal tumorigenesis. Here the authors report that excessive mtROS induces the release of mitochondrial PGAM5 into ...

After a windswept final round he described as “super, super tough”, New Zealand’s Josh Geary clinched the 2025 Vic Open at 13th Beach Golf Links. Our team is in place at 13th Beach to report on the ...

Trial registration ClinicalTrials.gov identifier NCT00572143. Intensive follow-up after curative colon cancer resection is associated with improved overall survival of 5–10%. No international ...

Mean age was 35.8 (8.8) years. Overall, 26 patients (72.2%) had Crohn’s disease, 9 (25.0%) had ulcerative colitis and 1 (2.8%) had unspecified IBD; 23 (63.9%) were currently treated with biologic ...

Objectives Malignant bowel obstruction (MBO) is a common, challenging condition in advanced cancer ... Methods A prospective, interventional, single-arm, open label study of Gastrografin across two ...

Adenomatous polyps typically do not cause symptoms unless they progress to colon cancer. Even then, there may be no sign of a problem until the malignancy is advanced. This is why colon cancer ...

Background Laparoscopic adhesiolysis is emerging as an alternative for open surgery in adhesive small bowel obstruction. Retrospective studies suggest that laparoscopic approach shortens hospital ...

He is a native English speaker. A blood test that accurately detects colon cancer in middle-aged and older people and also rules it out when it is not present can help to increase the rate of ...

Leftenant-Colon became the first person in the family to pursue higher education, studying in the Bronx at the Lincoln School for Nurses, one of the first nursing schools open to African Americans.

Both lobectomy and segmentectomy demonstrated better outcomes than wedge resection, which had five-year OS of 66.3% and 10-year OS of 41.4%. This research highlights the profound effect of using ...

A comprehensive molecular and clinical study of patients with young-onset CRC. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal Cancers Symposium. This abstract does not include a ...

Refining colorectal cancer screening strategies using polygenic risk scores and classical risk factors: A proof-of-concept study in the UK Biobank cohort. Multivariable logistic regression model of ...