Fmoc（9-芴甲氧羰基）保护是一种常用的氨基保护策略，它可以在有机合成中保护氨基不受其他反应的影响。当提到Fmoc保护的G5-PAMAM时，意味着G5代的聚酰胺胺（PAMAM）树枝状大分子的氨基被Fmoc基团所保护。

定义与结构：PAMAM Dendrimer G2-SA 指的是第二代聚酰胺-胺型树枝状高分子，其表面或末端被琥珀酸（SA）官能团修饰。 特性：由于琥珀酸的引入 ...

概述：PAMAM (聚酰胺胺) 树枝状聚合物是一类具有高度分支和层次化结构的合成高分子，其中心通常由乙二胺或氨基化合物组成，呈现出密集的球状结构。以乙二胺为核的5.5代PAMAM树枝状聚合物，在结构上包含完整的五代分支及半代的末端基团。半代的特性源于 ...

一、树枝状大分子PAMAM在生物医药领域应用进展：树枝状大分子聚酰胺胺（PAMAM）是迄今为止研究地较为广泛的树形大分子之一。早在 20 世纪 90 年代Tomalia ...

Nanomedicine. 2012;7(8):1225-1233. Most of the strategies described for the passage of drugs across the BBB can be enhanced by nanotechnology and some of the mechanisms involved include: NPs open ...

PAMAM dendrimers can hold DNA in cavities and act as nonimmunogenic vectors for in vivo gene transfer. The combination of a gene and NP with a surfactant coating can facilitate gene transfer in ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...

Nanotechnology Laboratory, TRANSCEND Research Center, Regional Institute of Oncology, 2-4 General Henri Mathias Berthelot, Street, Iaşi 700483, Romania Department of Bioinformatics, TRANSCEND Research ...