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CHI3L1—— 膀胱癌进展与 M2 巨噬细胞关联的关键 “密码” 及潜在治疗 ...
此外,CHI3L1 下调还可增加 BCa 细胞对吉西他滨(gemcitabine,GEM)的敏感性。 PTX 通过抑制 CHI3L1 减弱 BCa 细胞增殖、迁移和侵袭:使用 FDA 批准的 CHI3L1 特异性抑制剂己酮可可碱(pentoxifylline,PTX)进行实验,结果显示 PTX 能抑制 J82 和 UMUC3 细胞的生长,IC50 分别为 6. ...
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