ESO-T01 is the first in vivo BCMA CAR-T candidate to reach the clinical stageEarly clinical data are expected in second half of ...

Additionally, functional assay with bone marrow-derived macrophages (BMDMs) shows that ENT significantly enhances tumor cell phagocytosis and antigen presentation, increasing the proliferation of ...

This call prompts the immune system to investigate, leading to enhanced immune cell migration, phagocytosis, antigen processing, MHC loading, maturation, and the cross-priming of T cells. This ...

9Experimental and Translational Pathology Platform, AMMICa, INSERM US23/UAR3655, Gustave Roussy, Villejuif, France. 20Department of Pathology, University Paris-Saclay, Gustave Roussy Cancer Center, ...

Neutrophils, monocytes and macrophages arise from common precursors, explaining much of their functional and phenotypical overlap. However, these cells also have complementary functions during the ...

Proof-of-concept study to evaluate the safety, tolerability and efficacy of MOv18 IgE in patients with platinum-resistant ovarian cancer ...

A significant challenge for chimeric antigen receptor (CAR) T cell therapy against glioblastoma (GBM ... Anti-EGFRvIII-SGRP CAR T cells eradicate orthotopic EGFRvIII-mosaic GBM in vivo, promoting ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

MOv18 IgE is an IgE antibody targeting the folate receptor alpha (FR alpha) antigen which is selectively ... cell-mediated cytotoxicity (ADCC) and phagocytosis (ADCP) and release pro-inflammatory ...

This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...