OSM-3, revealing that the kinase, NEKL-3, phosphorylates a serine/threonine patch at the hinge region of the motor to mediate autoinhibition until it reaches the ciliary middle segment. The findings ...

Here the authors show that Nicotiana benthamiana NbMPK3/6 can phosphorylate the tomato chlorosis virus P7 protein leading to suppression of callose-dependent antiviral defence. KSHV modifies ...

Differentially localized mTORC1 complexes phosphorylate distinct substrates in response to different amino acid supplies. FOXC1 transcription factor plays a role in vascular development ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Transient receptor potential vanilloid 1 ...

By exploring the conservation and functional diversity of RIPK3 and related RHIM-containing proteins across vertebrates, this important work sheds light on the evolutionary dynamics of these key ...

1Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. 2Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.