Transcriptomic analysis via RNA sequencing revealed an aberrant activation of the cAMP-PKA-CREB pathway in offspring exposed to BPA. The use of H89, a selective PKA inhibitor, effectively rescued the ...

If you get into working on bigger puzzles, they can eat up your dining room table, coffee table or desk space for long stretches of time. This is why many jigsaw fans have a dedicated puzzle ...

Over the last decade, there has been a growing perception of the complexity associated with FSH-induced cellular signaling. It is now clear that the canonical Gs/cAMP/PKA pathway is not the sole ...

Will it be a record-growing 36th La Liga title for Real Madrid, the defending champions of Spain’s top-flight? Barcelona are leading the chase for the crown, having won in 2022-23, while Madrid derby ...

Both of these reports lacked pH measurements and interpretation of drug structures and pH and pKa values in relation ... which is a quaternary ammonium salt (see Table 3). e One OH group on ...

According to a new study published in the journal Cellular Signalling, cannabinoids may play a crucial role in preventing and treating brain diseases by regulating key physiological processes in the ...

Which AI-powered capability will dominate in the years ahead?

Striatal dopamine (DA) release regulates reward-related learning and behavioural activation and is believed to consist of a short-lived phasic and continuous tonic component. Here, we build a ...

1Department of Obstetrics and Gynecology, Peking University Third Hospital, China 2Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing, China. 3Biobank, Peking ...

direct inhibition of transformed-cell growth and inhibition of tumour angiogenesis and metastasis (Table 3). The use of cannabinoids in medicine, however, is severely limited by their psychoactive ...