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在研究结论与讨论部分，研究人员成功鉴定出一个由 26 个基因组成的高度精炼的特征集，这一特征集能够精准地刻画胃腺体中化生的存在和细胞特征。这些基因由异常上皮细胞表达，反映了化生灶中成熟和未成熟肠系细胞的情况，并且有望用于区分这些异常的细胞谱系。研究还发现，随着病变程度的加重，未成熟肠细胞标记物的表达逐渐增加，这进一步凸显了未成熟肠细胞在晚期癌前病变生物学过程中的重要作用。

To address this question, in this review, the available evidence on the role of gastric dysbiosis and chronic inflammation in precancerous conditions of the stomach is summarized, particularly ...