Prolactin is a polypeptide hormone whose major biological actions are related to normal lactation and reproduction. Abnormally high prolactin levels, referred to as hyperprolactinemia, can result ...

Progestin-only oral contraceptives prescribed or dispensed at discharge from the hospital to be started 2-3 weeks postpartum (e.g., the first Sunday after the newborn is 2 weeks old). Depot ...

AI molecular design tool for de novo design, scaffold hopping, R-group replacement, linker design and molecule optimization.

Serum concentrations of MEL, GN, testosterone (T) and prolactin (PRL) were determined at 30-min. intervals several hours prior to, during, and after MEL administration. Though serum MEL ...

An artificial intelligence model has created a new protein that researchers say would have taken 500 million years to evolve in nature — if nature were capable of producing such a thing.

Small-molecule ligand regulators targeting TSHR have great potential for treating TSHR ... and other physiological functions as a neurotransmitter or modulator. TRH regulates prolactin secretion in ...

The drug restored the cholinergic system and improved memory,” added Moreno. Rafael Rodríguez believes that “this molecule could become a drug to treat the symptoms of dementia, at least during the ...

Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were originally thought to be intracellular signaling pathways that mediate cytokine signals in mammals. Existing ...

Two approaches proposed to overcome this problem are: the indirect method, which measures a combination of several factors in the biological cascade affected by administration of GH; and the direct ...

Despite being a first-line treatment for adolescent depression and anxiety, antidepressant drugs appear to have questionable efficacy and carry an increased risk of adverse effects in this ...

The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of ...