The EMA’s Committee for Medicinal Products for Human Use (CHMP) determined that expected clinical benefits of seladelpar include delayed development of liver fibrosis and cirrhosis, potentially ...

Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that regulates intestinal inflammation. PPARγ is highly expressed in the colon and can be activated by various dietary ...

Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders.

Complete the form below to unlock access to ALL audio articles. In diabetes or obesity, insulin resistance in the myocardium ...

Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which proceeds slowly and cannot be ...

The PPARβ/δ factor is the most abundant member of the peroxisome proliferator-activated receptor (PPAR) family in the heart.

Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be ...

The approval of ursodeoxycholic acid (UDCA) for primary biliary cholangitis (PBC) in 1997 marked a pivotal turning point in ...

Trump’s summit meetings with Kim Jong Un, North Korea has become a nuclear power and a proliferator of weapons of mass ...

There are numerous trials revealing a blood pressure-lowering effect of thiazolidinediones in diabetic patients as well as in non-diabetic patients. Most of these studies are well designed but ...

PPARα = peroxisome proliferator-activated receptor alpha; LPS = lipopolysaccharide; ROS = reactive oxygen species. Impact on Adolescent Reproductive Health: The effects of alcohol on testosterone ...

but also by cautionary tales from past efforts to borrow from the diabetes armamentarium for asthma," like thiazolidinediones and peroxisome proliferator-activated receptor γ agonists ...