A research group of The University of Tokyo has discovered that in mammals, a protein kinase A (PKA) promotes wakefulness, ...

A new study reveals that eating two ounces of almonds daily can significantly aid exercise recovery by reducing muscle ...

Genzyme Corp. (Sanofi Genzyme) has identified receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors reported to be useful for the treatment of Alzheimer’s disease, multiple ...

Depression, particularly in women, often co-occurs with reproductive health conditions like dysmenorrhea or painful menstrual ...

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized primarily by the formation of heterotopic ...

PEG-MGF, or polyethylene glycol-modified mechanogrowth factor, is a peptide that has garnered attention in scientific ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Multiplexed assays of variant effect are an increasingly important tool in genetic research and including more context specificity in their design would aid interpretation and discovery.

生命科学Life science2024年11月21日，中山大学孙逸仙纪念医院蒋琳加研究员在Cell Press细胞出版社旗下期刊Trends in Cell Biology杂志发表了题为 “Targeting SHP1 and SHP2 to ...

Clinical data include analyses of novel, investigational therapies with the potential to help address unmet needs in sickle cell disease and hemophiliaNew data from the HIBISCUS phase 2 trial ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

A decade after the discovery of CALR, the results are the first for a possible therapy for CALR-mutated MPNs to reach the ...