A protein called Runx2 contributes to the abnormal activity of lung cells that drive pulmonary fibrosis, a new study shows.

Relative alveolar hypoventilation is directly related to the compensatory mechanisms that follow pulmonary vascular occlusion. Because of the mechanical block in the circulation, blood is diverted ...

Thirty-three cases of sarcoidosis (4.4% of 746 patients) showed an alveolar radiological pattern. A study of pulmonary function was carried out in 25 patients and compared with that of 46 patients ...

Introduction: Pulmonary alveolar proteinosis (PAP) is a rare disease in infancy characterized by the accumulation of lipoprotein material within the alveoli, leading to impaired gas exchange, ...

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Methods: Protein permeability and the expression of TJ proteins were assessed in vivo in wild-type and Fas-deficient lpr mice 16 hours after the intratracheal instillation of recombinant human soluble ...

Savara is on track for potential approval by the end of 2025 for MOLBREEVI™s in autoimmune pulmonary alveolar proteinosis (aPAP), assuming the treatment receives priority review. The company has ...

By analyzing multiple emphysema and COPD patient datasets, SPP1 is significantly upregulated in the lungs of patients, ...

Our lead program, MOLBREEVI*, is a recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis (aPAP).

The Broad Institute and Illumina today announced their intent to collaborate on a groundbreaking Spatial Flagship Project, ...

An international team of researchers has, for the first time, created a detailed map of the location and identity of individual cells in the adult lung, both from healthy lungs and in lungs from ...