The paper introduces DeepTX, a valuable deep-learning framework linking stochastic, mechanistic modelling with single-cell RNA sequencing data to investigate transcriptional burst kinetics on a genome ...
Non-steroidal anti-inflammatory drugs (NSAIDs) and traditional disease modifying antirheumatic drugs (DMARDs) are widely used in the treatment of psoriatic arthritis (PsA), but this is based more upon ...
This useful study highlights the largely redundant role of the decapping activators Edc3 and Scd6 in orchestrating post-transcriptional programs to modulate metabolic responses to nutrients in yeast.