Today, Grünenthal announced that the first participants have been enrolled in a first-in-human Phase I clinical trial for a nociceptin (NOP) receptor agonist. The trial will include 90 healthy ...

A research team led by Prof. Zhou Rongbin from the University of Science and Technology of China (USTC) discovered the ...

1 Department of Hematology, Zhuji Affiliated Hospital of Wenzhou Medical University, Zhuji, Zhejiang, China 2 Department of Breast Surgery, Zhuji Affiliated Hospital of Wenzhou Medical University, ...

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing ...

The granted patent US12049488B2 describes a modular synthetic receptor designed for specific ligand binding and functional activity initiation. The receptor consists of three main components: an ...

Coave's proprietary ALIGATER platform enables specific retargeting of AAV vectors to human receptors via a one-step chemical conjugation of peptide-based ligands at the surface of the capsid, ...

Tool for directed evolution of protein receptors specifically for a ligand of interest ; implementation and fine-tuning of @zaixizhang 's PocketGen focused on maximizing binding affinity.

The aim of this project is to identify and develop novel inhibitors targeting HBV DNA Polymerase and HBx Protein through Molecular Docking to block viral replication and progression of Hepatitis B.