Researchers uncover sex-specific pain management mechanisms, revealing men rely on endogenous opioids while women use ...

What’s more, AM-101 improved radiation treatment, slowing down the growth of NSCLC subcutaneous xenograft tumors in mice, by ...

Tectonic Therapeutic's lead candidate TX45 showed positive phase 1 results for Group 2 Pulmonary Hypertension. Read why I ...

New, non-hallucinogenic versions of psychedelics are blurring the boundaries of the drug trip.

Through experiments on mice infected with a herpes virus, scientists discovered an immune system sensor that detects viral ...

Although a combination of certain pain medications has been found to be more effective than opioids alone at managing ...

SAP is required for signalling downstream of members of the signalling lymphocytic activation molecule (SLAM) family of immunomodulatory receptors. Examination of humoral responses in SAP ...

Blocking inhibitory receptors like PD-1 and CTLA-4 has revolutionized cancer treatment in recent years. However, despite major successes in melanoma and lung cancer, the majority of cancer types are ...

The authors developed a bioinformatic pipeline to aid the screening and identification of inhibitory receptors suitable as drug targets. The challenge lies in the large search space and lack of tools ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Androgen receptors play a crucial role in male and female reproduction, influencing various aspects of fertility and reproductive health. In the context of reproductive physiology, androgen receptors ...

A new molecule, based on llama antibodies, could counteract opioid effects by preventing drugs from binding to brain ...