Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...

A study identifies "proteolethargy," reduced protein mobility caused by oxidative stress, as a unifying mechanism in chronic ...

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of ...

Researchers hope findings will lead to new class of drugs for many different diseases for which proteolethargy is a common ...

Healthcare - The exploration of peptides as bioregulatory molecules has gained considerable attention in recent years, with a ...

Celebrating 10 years of the CUNY Research Scholars Program, the Ad Astra Undergraduate Research Newsletter released a special 10 year edition highlighting CRSP student, alumni, and faculty research ...

However, it is now recognized that some ROS, particularly hydrogen peroxide (H₂O₂), play a crucial role as signaling molecules, essential for maintaining health. These oxidative signals activate ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...