This valuable study reports on the critical role of ANKRD5 (ANKEF1) in sperm motility and male fertility. However, the supporting data remain incomplete. This work will be of interest to biomedical ...

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

China: A recent study published in the Journal of Diabetes and its Complications highlighted dapagliflozin's (DAPA) ...

23. Dahiya D, Mackin C, Nigam PS. Studies on bioactivities of Manuka and regional varieties of honey for their potential use ...

Overexpression of SY1 decreased mitochondrial membrane potential (indicated by Rho 123 fluor intensity), increased cellular ROS levels (indicated by DCF mean intensity) and reduced cell viability ...

For detection of mitochondrial reactive oxygen species (ROS), cells were stained with MitoSOX Red (Invitrogen) on days 2 and 3 of cell differentiation, for measurement of mitochondrial membrane ...

School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University; Institute of Biomedical Innovation, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330031, China Center ...

Conclusions These results describe a novel pathway where altered mitochondrial biology in JDM CD14+ monocytes lead to oxmtDNA production and stimulates ISG expression. Targeting this pathway has ...

Department of Critical Care Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, People’s Republic of China ...

Diabetic cardiomyopathy (DCM) is a specific heart condition in diabetic patients, which is a major cause of heart failure and significantly affects quality of life. DCM is manifested as abnormal ...

which manifests as mitochondrial swelling and cristae re-modeling, decreased membrane potential, impaired ATP production, and excessive ROS and release of pro-apoptotic factors (Pickles et al., 2018).