The potential of monoclonal antibodies (mAbs) as therapies is indisputable. The current mAbs market is expected to be around ~USD 150 billion. In 2021, five out of the top 10 selling drugs were ...

Differentially expressed genes (DEGs) of EPO-treated fibroblast-like synoviocyte (FLS) were screened by transcriptome sequencing. The transcription factor of neuraminidase 3 (NEU3) of DEGs was ...

An ANA blood test (antinuclear antibody test) is usually performed on a blood sample as part of the diagnostic process for certain autoimmune diseases. It is usually ordered along with other blood ...

Immunoglobulin G (IgG) antibodies are a critical component of the adaptive immune system, binding to and neutralizing pathogens and other foreign substances. Recent advances in molecular antibody ...

They are a type of medical treatment. Scientists make monoclonal antibodies, or mAbs, in a lab. They work like the natural antibodies your body makes to fight illness. They go out into your body ...

Researchers from the University of Pittsburgh and NIH developed a broadly neutralizing antibody that protects monkeys from severe H5N1 avian flu by targeting a stable region of the virus, reducing the ...

这一过程由 Na?/H?逆向转运体 NHE1、神经氨酸酶 Neu1 和 Neu3 介导，其起始需要 pH 触发的唾液酸的酶促去除，因为唾液酸的存在会阻碍半乳糖凝集素的结合。去唾液酸化的糖蛋白随后逆向运输至高尔基体，在那里其聚糖组成被重置，从而调节 EGF 依赖的侵袭性细胞 ...

[11–13] Testing for Sialidase Activity The BVBlue® (Gryphus Diagnostics, AL, USA) system is a chromogenic diagnostic test based on the presence of elevated sialidase enzyme activity in vaginal ...

对参与 Neu5Ac 代谢的 33 个基因在幼体发育过程中的表达分析发现，在变态发育阶段，参与唾液酸去除的 3 个神经氨酸酶基因（neu1、neu3、neu3.1）表达增加，这表明唾液酸的去除是一个在变态发育过程中建立的主动过程，有助于幼体安全进入海葵。 预测 4：海葵 ...