Quantitative Biology Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, ...

Rationally Screen for, Discover & Validate Novel Chemical Starting Points to Develop Robust Induced Proximity of Protein-Protein Interactions Platforms that Successfully Translate into the Clinic ...

Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China ...

These molecules are designed to self-assemble to form the full bifunctional degrader at the intended location in the body. Their small size greatly facilitates oral bioavailability and the ability ...

Kesmalea’s SELFTAC® platform is designed to solve the ‘size problem’ of large, bifunctional protein degraders by transforming them into small molecules SELFTAC drug candidates will combine oral dosing ...

Kesmalea’s SELFTAC® platform is designed to solve the ‘size problem’ of large, bifunctional protein degraders by transforming them into small molecules SELFTAC drug candidates will combine ...

According to Professor Michael Strano, “Instead of making a spaghetti-like molecule, we can make a sheet-like molecular plane, where we get molecules to hook themselves together in two ... The main ...