For in vitro GPX4 deletion, enriched CD8 + T cells from Gpx4 fl/fl-ERT2Cre-P14 mice were treated with 5 μM 4 ... following manufacturer’s instructions. Viral load in specific tissues (spleen and brain ...

Sub cluster analysis of T cells resolved naive (CD4+ and CD8+), CD4+ effector T cells, CD8+ cytotoxic T cells and γδ T cells. Cross species analysis revealed a high conservation of T cell subsets ...