Briola and co-authors determined the structure of the human CTF18 clamp loader bound to PCNA to high resolution, analyzed the structure, and tested a new mechanism involving a human-specific Ctf18 ...

AI has led to breakthroughs in synthetic biology, whose promise ranges from new drugs that perform better to replacements for ...

Next-generation sequencing allows for critical insights into gene therapy products, which can help streamline and accelerate ...

Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States International Institute for Nanotechnology, Northwestern University, Evanston, Illinois 60208, United States ...

These ‘letters’ are shorthand for the four molecules—adenine (A), thymine (T), cytosine (C), and guanine (G)— that ... But the same genetic sequence, depending on its structure, can also recruit the ...

Sarkies et al take the innovative approach of introducing enzymatic genome-wide cytosine methylation system (DNA methyltransferases, DNMTs) into E. coli, which normally lacks such a system. They ...

By using three broad types of measurements—working capital, asset performance, and capital structure—you may evaluate the strength of a company's balance sheet and, thus, its investment quality.