In a 2015 study, Graybiel found that one of these cell types, D1, sends input to the substantia nigra, which is the brain’s major dopamine-producing center. It took much longer to trace the ...

The following is a summary of “Association of Striatal Dopamine Depletion and Brain Metabolism Changes With Motor and ...

Substantia nigra. Illustration showing a healthy substantia nigra in a human brain. The substantia ... [+] nigra plays an important role in reward, addiction, and movement. Degeneration of this ...

Dopaminergic neurons within the substantia nigra pars compacta (SnC) possess a distinct physiological phenotype from most other neurons within the brain. They are autonomously active, and generate ...

University of Southern California-led researchers have discovered the structural details of a brain receptor called GPR6, ...

Parkinson's symptoms mainly result from the death or impairment of dopamine-producing neurons in the brain's substantia nigra, a region involved in fine motor control. This is thought to be caused ...

These symptoms arise after substantial loss of the dopamine-producing cells in an area of the brain known as the substantia nigra. The 12-month trial, which is funded by an award from charity Cure ...