Adding fluorine to drug molecules can be tricky, but is often worthwhile. Rachel Brazil talks to the chemists trying to tame ...

Structures of some of the most important benzodiazepine derivatives commercially available. All reagents and solvents were used as purchased from Sigma-Aldrich (São Paulo, Brazil) without further ...

Dietary measures and medications may help reduce uric acid and manage gout. Gout can occur when blood uric acid levels are too high, causing crystals to form in the toes, feet, and other joints.

N-Hydroxysuccinimide can also form an intermediate smoothly, but the intermediate requires purification. Therefore, N,N′-carbonyldiimidazole was used in the current study to react with carboxylic acid ...

Uric acid is a waste product found in urine. If your body makes too much or doesn't eliminate enough of it, uric acid levels can become too high—a condition known as hyperuricemia. High uric acid ...

A recent breakthrough by researchers from Shinshu University, Japan, is changing this landscape. The team has successfully achieved the first total synthesis of inaoside A, a natural compound found in ...

Malic acid benefits can include acne treatment, and skin care such as exfoliation and hydration. It is an alpha hydroxy acid, found naturally in fruits and wines and used as an ingredient in ...

The F11 bacteria also broke down a substantial portion of two additional types of PFAS after 100 days: 58% of 5:3 fluorotelomer carboxylic acid and 21% of 6:2 fluorotelomer sulfonate. "The bond ...

Our results confirm that these routes have the potential to outperform the business-as-usual (BAU) pathway, both economically and environmentally, under specific feedstock scenarios, setting the path ...

Department of Pharmaceutical Technology, Federal Fluminense University─UFF, Niteroi, Rio de Janeiro 24241-000, Brazil Institute of Chemistry, Federal Fluminense University─UFF, Niteroi, Rio de Janeiro ...