Tumor suppressor genes make proteins that regulate the growth of cells, and they play an important role in preventing the development of cancer cells. When tumor suppressor genes are altered or ...
"I think it's fascinating that an aspect of how p14 ARF acts as a tumor suppressor is through immobilization of the liquid-like nucleolus and apparent inhibition of critical steps in ribosome ...
These mechanisms, including those involving the tumor suppressor protein p53, are widely studied due to their critical role in disease. Through studies of proteins that regulate p53, scientists at St.