Such synapses have been regularly discarded for further analysis in previous synaptosome studies (e.g. Martinez-Sanchez 2021). Whilst the targeting approach using a fluorescent PSD95 marker is novel ...

In addition to its canonical role as a neurotrophin-3 receptor tyrosine kinase, postsynaptic TrkC promotes excitatory synapse organization through interaction with presynaptic receptor-type tyrosine ...

Alzheimer’s disease (AD) is a progressive neurocognitive disorder and the most common cause of dementia in the elderly. Plaques of amyloid-β (Aβ) peptides and neurofibrillary tangles of ...

Commenting on the Spinogenix glaucoma program, and his addition to the Company's SAB, Dr. Weinreb noted, "Glaucoma-related ...

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Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single molecules may have ...

This monoinnervating synapse emerges during development as multiple inputs are eliminated ... Loss of C1q did not affect microglia-dependent calyceal pruning. Excitatory and inhibitory synaptic ...