B, a transcription factor, is essential for maintaining X chromosome inactivation in T cells, connecting immune activation to ...

CAR T-cell manufacturing involves T-cell apheresis, CAR transduction, and expansion of transduced autologous or allogeneic T cells. To date, approved CAR T-cell products rely on lentiviral ...

CAR T-cell therapy is a type of immunotherapy. CAR stands for chimeric antigen receptor. You might also hear it called a type of adoptive cell transfer. CAR T-cell therapy is a very complex and ...

Survival rates for aggressive lymphomas have improved significantly thanks to advances in treatment, such as chimeric antigen receptor-T cell therapy (CAR-T cell therapy). Dr. Madiha Iqbal ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study.